Table 1.

Criteria for defining the composite definition of severe asthma clinical remission used in the pooled post hoc analysis by Menzies-Gow et al. [1] and comparison with the reference Delphi documents [5, 6]

Items	Composite definition of severe asthma clinical remission used by Menzies-Gow et al. (all criteria needed) [1]	Severe asthma remission and/or super-responder criteria from Delphi processes [5, 6]	Consistency
Daily symptoms	ACQ score ≤ 0.75 at 6 and 12 months	ACQ score ≤ 0.75 or < 1.0 for ≥ 12 months	Yes at 12 months, no at 6 months
Exacerbation	Zero exacerbations at 6 and 12 months	Exacerbation elimination for ≥ 12 months	Yes at 12 months, no at 6 months
OCS	Zero OCS use at 6 and 12 months	Cessation of maintenance OCS for ≥ 12 months	Yes at 12 months, no at 6 months
Lung function	Pre-BD FEV1 increase ≥ 100 mL at 6 and 12 months	≥ 500 mL improvement in FEV1 for ≥ 12 months	No

ACQ Asthma Control Questionnaire, BD bronchodilator, FEV₁ forced expiratory volume in 1 s, OCS oral corticosteroids