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. 2022 Jun 14;39(8):3472–3487. doi: 10.1007/s12325-022-02169-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 3 — Treatment algorithm: prescribing SGLT2is for HFrEF in clinical practice by cardiologists: patient assessment, treatment initiation, monitoring, and patient counseling [23, 24, 37, 53–55]. Modified from Vardeny O, Vaduganathan M. Practical guide to prescribing sodium-glucose cotransporter 2 inhibitors for cardiologists. JACC Heart Fail 2019;7:169–172, ©2019, with permission from Elsevier Inc. DKA diabetic ketoacidosis, eGFR estimated glomerular filtration rate, HCP healthcare provider, HFrEF heart failure with reduced ejection fraction, LVEF left ventricular ejection fraction, NYHA New York Heart Association, QD once daily, SGLT2i sodium–glucose cotransporter 2 inhibitor, T2D type 2 diabetes