Table 3.
Univariable and multivariable analysis of risk factors for PACG without prior ANA diagnosis.
| Prior ANA Diagnosis |
No Prior ANA Diagnosis |
Univariable Analysis | Multivariable Analysis | |||
|---|---|---|---|---|---|---|
| N (%) | N (%) | OR (CI) | P value | OR (CI) | P value | |
| Age [years] | ||||||
| <40 | 87 (12.2) | 624 (87.8) | 2.35 (1.84-3.03) | <0.001 | 2.08 (1.62-2.70) | <0.001 |
| 40-59 | 433 (24.7) | 1321 (75.3) | REF | REF | ||
| 50-59 | 1141 (24.9) | 3445 (75.1) | 0.99 (0.87-1.12) | 0.873 | 0.99 (0.87-1.13) | 0.916 |
| 60-69 | 2215 (25.9) | 6325 (74.1) | 0.94 (0.83-1.05) | 0.275 | 0.89 (0.79-1.01) | 0.077 |
| 70-79 | 2775 (26.7) | 7634 (73.3) | 0.90 (0.80-1.01) | 0.083 | 0.90 (0.79-1.02) | 0.105 |
| 80+ | 1062 (21.1) | 3982 (78.9) | 1.23 (1.08-1.40) | 0.002 | 1.28 (1.11-1.47) | 0.001 |
| Sex | ||||||
| Female | 5222 (26.6) | 14386 (73.4) | REF | REF | ||
| Male | 2490 (21.8) | 8941 (78.2) | 1.30 (1.23-1.38) | <0.001 | 1.32 (1.25-1.40) | <0.001 |
| Race | ||||||
| Non-Hispanic White | 4551 (25.0) | 13674 (75.0) | REF | REF | ||
| Asian | 633 (26.7) | 1741 (73.3) | 0.92 (0.83-1.01) | 0.074 | 0.96 (0.87-1.07) | 0.477 |
| Black | 814 (20.7) | 3116 (79.3) | 1.27 (1.17-1.39) | <0.001 | 1.25 (1.15-1.37) | <0.001 |
| Hispanic | 1107 (28.0) | 2845 (72.0) | 0.86 (0.79-0.92) | <0.001 | 0.85 (0.78-0.92) | <0.001 |
| Unknown | 608 (23.7) | 1955 (76.3) | 1.07 (0.97-1.18) | 0.171 | 0.99 (0.85-1.17) | 0.938 |
| Gonioscopy | ||||||
| Yes | 6043 (31.0) | 13476 (69.0) | REF | REF | ||
| No | 1670 (14.5) | 9855 (85.5) | 2.63 (2.50-2.78) | <0.001 | 2.50 (2.38-2.70) | <0.001 |
| Education | ||||||
| High school or less | 2003 (23.5) | 6529 (76.5) | REF | REF | ||
| Some college | 3804 (25.0) | 11410 (75.0) | 0.92 (0.86-0.98) | 0.009 | 0.97 (0.91-1.04) | 0.418 |
| College graduate | 1493 (27.2) | 3990 (72.8) | 0.82 (0.76-0.89) | <0.001 | 0.93 (0.85-1.02) | 0.121 |
| Unknown | 413 (22.8) | 1402 (77.2) | 1.04 (0.92-1.18) | 0.509 | 1.02 (0.82-1.26) | 0.861 |
| Income | ||||||
| <$50k | 2140 (23.5) | 6985 (76.5) | REF | - | ||
| $50-$100K | 2372 (25.5) | 6925 (74.5) | 0.89 (0.84-0.96) | 0.001 | - | |
| >$100K | 1991 (26.7) | 5475 (73.3) | 0.84 (0.79-0.90) | <0.001 | - | |
| Unknown | 1210 (23.5) | 3946 (76.5) | 1.00 (0.92-1.08) | 0.983 | - | |
| Worth | ||||||
| <$149k | 2266 (23.4) | 7438 (76.6) | REF | REF | ||
| $150-499K | 2002 (24.9) | 6047 (75.1) | 0.92 (0.86-0.99) | 0.018 | 0.95 (0.88-1.02) | 0.173 |
| 500K+ | 2289 (27.3) | 6100 (72.7) | 0.81 (0.76-0.87) | <0.001 | 0.90 (0.83-0.98) | 0.012 |
| Unknown | 1156 (23.6) | 3746 (76.4) | 0.99 (0.91-1.07) | 0.756 | 0.94 (0.85-1.04) | 0.203 |
| Insurance | ||||||
| HMO | 3862 (25.5) | 11268 (74.5) | REF | REF | ||
| PPO | 938 (23.0) | 3137 (77.0) | 1.15 (1.06-1.24) | 0.001 | 1.12 (1.02-1.22) | 0.013 |
| EPO | 402 (21.0) | 1516 (79.0) | 1.29 (1.15-1.45) | <0.001 | 1.38 (1.22-1.56) | <0.001 |
| Other | 2511 (25.3) | 7410 (74.7) | 1.01 (0.95-1.07) | 0.702 | 1.00 (0.93-1.07) | 0.949 |
| Location | ||||||
| Northeast | 2078 (28.3) | 5275 (71.7) | REF | REF | ||
| South | 3108 (22.8) | 10539 (77.2) | 1.34 (1.25-1.42) | <0.001 | 1.30 (1.22-1.40) | <0.001 |
| Midwest | 1348 (24.8) | 4087 (75.2) | 1.19 (1.10-1.29) | <0.001 | 1.13 (1.03-1.23) | 0.007 |
| Mountain | 441 (28.3) | 1116 (71.7) | 1.00 (0.88-1.13) | 0.960 | 0.99 (0.87-1.13) | 0.887 |
| Pacific | 731 (24.2) | 2292 (75.8) | 1.24 (1.12-1.36) | <0.001 | 1.27 (1.16-1.36) | <0.001 |
| Total observability | ||||||
| Mean (SD) [years] | 3.9 (2.5) | 3.2 (2.1) | 0.88 (0.87-0.89) | <0.001 | 0.88 (0.87-0.89) | <0.001 |
Statistically significant p-values and odds ratios are bolded; OR = odds ratio; CI = Confidence Interval; EPO = exclusive provider organization; HMO = health maintenance organization; PPO = preferred provider organization.