Table 3.
Examine the prognosis of NCAPG2 in LGG patients analysis by cox regression.
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| WHO grade | 466 | ||||
| G2 | 223 | ||||
| G3 | 243 | 3.059 (2.046-4.573) | <0.001 | 1.991 (1.280-3.097) | 0.002 |
| IDH status | 524 | ||||
| WT | 97 | ||||
| Mut | 427 | 0.186 (0.130-0.265) | <0.001 | 0.341 (0.214-0.543) | <0.001 |
| 1p/19q codeletion | 527 | ||||
| codel | 170 | ||||
| non-codel | 357 | 2.493 (1.590-3.910) | <0.001 | 1.703 (1.008-2.878) | 0.047 |
| Histological type | 332 | ||||
| Oligoastrocytoma | 134 | ||||
| Oligodendroglioma | 198 | 0.845 (0.527-1.352) | 0.482 | ||
| Age | 527 | ||||
| <=40 | 264 | ||||
| >40 | 263 | 2.889 (2.009-4.155) | <0.001 | 2.872 (1.875-4.400) | <0.001 |
| Gender | 527 | ||||
| Female | 238 | ||||
| Male | 289 | 1.124 (0.800-1.580) | 0.499 | ||
| NCAPG2 | 527 | 1.763 (1.465-2.121) | <0.001 | 1.302 (1.032-1.642) | 0.026 |