Table 2.
Antibiofilm effect of Cinnamomum and its derivative compounds against biofilm of bacteria associated with dental disorders.
| Year of publication (references) | Cinnamomum species | Cinnamomum ingredients | Microorganism | Biofilm model | Outcome |
|---|---|---|---|---|---|
| 2021 ( Worreth et al., 2021 ) |
NR | Cinnamaldehyde | Streptococcus mutans Streptococcus mitis | Cellulose-based material | Decreased bacterial growth and biofilm formation on cellulose-based dental clear aligners. |
| 2021 ( Mala et al., 2021 ) |
Cinnamomum | NR | Streptococcus mutans | Microplates | Inhibited biofilm formation |
| 2021 ( Dos Santos et al., 2021 ) |
NR | Cinnamaldehyde |
Streptococcus mutans Lactobacillus casei Fusobacterium nucleatum
Actinomyces israelii Enterococcus faecalis |
Microplates | Curcumin- cinnamaldehyde hybrids showed an antibiofilm effect against oral pathogens. |
| 2021 ( Jeong et al., 2021 ) |
C. verum EO nanoemulsion | NR | Aciduric bacteria that cause dental caries. | Microcosm biofilm model | Suppressed oral microorganisms’ growth in biofilms and multi-species oral biofilms maturation. |
| 2020 ( De Oliveira Carvalho et al., 2020 ) |
C. zeylanicum EO | NR | Streptococcus mutans | Microplates | The C. zeylanicum EO antibiofilm activity against S. mutans was not significant compared to the control. |
| 2018 ( Ribeiro et al., 2018 ) |
NR | Citronellol, cinnamic acid, and cinnamaldehyde | Streptococcus mutans | Microplates | These substances inhibited the planktonic and biofilm community of S. mutans |
| 2018 ( Wang et al., 2018 ) |
C. zeylanicum EO | Cinnamaldehyde | Porphyromonas gingivalis | Microplates | C. zeylanicum EO and cinnamaldehyde suppressed biofilm formation of P. gingivalis by 74.5% and 67.3%, separately. However, only C. zeylanicum EO reduced preformed biofilms by 33.5%. |
| 2017 ( Zaltsman et al., 2017 ) |
NR | Cinnamaldehyde-modified particles | Streptococcus mutans | Resin material | This particle showed antibiofilm activity. |
| 2005 ( Filoche et al., 2005 ) |
Cinnamomum | NR | Streptococcus mutans, Lactobacillus plantarum | Microplates | The chlorhexidine amount needed to inhibit the bacterial biofilm was decreased in combination with Cinnamomum. |
NR, not reported; EO, essential oil.