Figure 1.

Association of serum irisin levels and features related to subclinical atherosclerosis and cardiovascular disease-related features in axSpA. Lower levels of irisin in patients with carotid plaques (A) and in patients with an atherogenic index (AI) ≥4 (B). Positive correlation between serum irisin and C-peptide levels (C). Results shown in (A) and (B) were obtained after linear regression analysis, while results shown in (C) were obtained after Pearson’s partial correlation test, in all the cases adjusting for sex, age at the time of the study and classical cardiovascular risk factors.