Table 3.

miRNAs significantly enriched in melanoma-derived EVs compared to NHEM originated EVs.

miRNA	RPMNHEM EVs	RPMmelanoma EVs	log2 foldenrichment	adj. p-value
hsa-miR-181c-5p	n.d.	72.44	n.c.	n.c.
hsa-miR-7704	22.46	1846.05	6.36	0.0285
hsa-miR-941	8.88	169.51	4.26	0.0340
hsa-miR-17-3p	26.68	110.37	2.05	0.0382
hsa-miR-140-5p	241.76	652.42	1.43	0.0499
hsa-miR-125b-5p	4714.05	12372.22	1.39	0.0280
hsa-miR-221-3p	9615.86	20975.48	1.13	0.0271
hsa-miR-374a-5p	332.45	711.86	1.10	0.0458
hsa-miR-24-3p	10575.16	22418.29	1.08	0.0325
hsa-miR-183-5p	1767.06	3678.38	1.06	0.0379
hsa-miR-92b-3p	1770.45	3612.54	1.03	0.0141
hsa-miR-30a-3p	672.22	1365.21	1.02	0.0380
hsa-miR-584-5p	924.33	1794.89	0.96	0.0455
hsa-miR-182-5p	2785.11	4923.31	0.82	0.0290
hsa-miR-99b-5p	3726.77	5271.35	0.50	0.0135
hsa-miR-574-5p	782.71	1078.30	0.46	0.0386

n.d., not detected; n.c., not calculated.