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. 2022 Jul 11;13:848508. doi: 10.3389/fphys.2022.848508

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Copyright © 2022 Liu, Wang, Chang, Bhetuwal, Bhattarai and Ni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pearson correlation analysis of bile acids and neonatal birthweights. (A) Quantitative analysis of neonatal weights in natural delivery control and the ICP group. Values representing the mean ± SEM, p values are presented with ^*** p < 0.001 vs. controls. (B,C) Correlation analysis of bile acids and neonatal weights in the two groups, respectively. (D) Correlation analysis of each bile acid and neonatal weight in ICP patients with a normal delivery according to the mass spectrometric data, respectively. Blue (dotted lines) and gray (solid lines) circles represent negative and no correlations, respectively. The 95% confidence interval for the linear regression is represented by the gray area.