Table 1.

Characteristics of the included subjects.

	HC	Moderate MDD	p-valuea	Severe MDD	p-valueb	Total MDD	p-valuec
Number	131	78	–	52	–	130	–
Age	37.07 (14.22)	35.77 (13.92)	0.80	37.88 (15.5)	0.93	36.61 (14.57)	0.79
Sex (F/M)	89/42	53/25	0.99	35/17	0.93	88/42	0.96
BMI	21.95 (3.48)	21.76 (2.42)	0.96	21.70 (2.70)	0.94	21.74 (2.52)	0.57
HDRS	0.48 (0.83)	20.47 (2.26)	<0.00001	29.27 (3.70)	<0.00001	23.99 (5.21)	<0.00001
Medication	0/131	13/65	<0.00001	8/44	<0.00001	21/109	<0.00001

^ap-value was from HC vs. moderate MDD; ^bp-value was from HC vs. severe MDD; ^cp-value was from HC vs. total MDD.

HC, healthy controls; MDD, major depressive disorder; F, female; M, male; BMI, body mass index; HDRS, Hamilton Depression Rating Scale.