Table 2.
Differential genera responsible for discriminating moderate MDD patients from HC.
| Genus | VIP | FC | Phylum |
|---|---|---|---|
| Enterorhabdus | 1.24 | 0.06 | Actinobacteriota |
| Olsenella | 1.34 | 0.1 | Actinobacteriota |
| Corynebacterium | 1.01 | 0.14 | Actinobacteriota |
| Psychrobacter | 1.04 | 0.15 | Proteobacteria |
| Slackia | 1.43 | 0.17 | Actinobacteriota |
| Parvimonas | 1.54 | 0.19 | Firmicutes |
| Porphyromonas | 1.31 | 0.2 | Bacteroidota |
| Gordonibacter | 1.95 | 0.22 | Actinobacteriota |
| Enterococcus | 1.02 | 0.22 | Firmicutes |
| Peptoniphilus | 1.51 | 0.26 | Firmicutes |
| Eggerthella | 1.26 | 0.28 | Actinobacteriota |
| Acetanaerobacterium | 1.07 | 0.3 | Firmicutes |
| Anaerotruncus | 2.11 | 0.31 | Firmicutes |
| Oxalobacter | 1.66 | 0.31 | Proteobacteria |
| Anaerofustis | 1.37 | 0.32 | Firmicutes |
| Allisonella | 1.21 | 0.32 | Firmicutes |
| Anaerococcus | 1.06 | 0.41 | Firmicutes |
| Eubacterium | 1.45 | 0.42 | Firmicutes |
| Barnesiella | 1.37 | 0.42 | Bacteroidota |
| Collinsella | 2.22 | 0.45 | Actinobacteriota |
| Actinomyces | 1.08 | 0.49 | Actinobacteriota |
| Odoribacter | 1.34 | 0.5 | Bacteroidota |
| Flavonifractor | 1.46 | 0.5 | Firmicutes |
| Coprobacillus | 1 | 0.53 | Firmicutes |
| Blautia | 1.83 | 0.66 | Firmicutes |
| Parabacteroides | 1.74 | 0.67 | Bacteroidota |
| Alistipes | 1.47 | 0.8 | Bacteroidota |
| Butyricimonas | 1.53 | 0.85 | Bacteroidota |
| Dorea | 1.02 | 0.85 | Firmicutes |
| Faecalibacterium | 1.19 | 1.32 | Firmicutes |
| Prevotella | 1.24 | 1.46 | Bacteroidota |
| Klebsiella | 1.14 | 2.39 | Proteobacteria |
| Megamonas | 1.19 | 2.51 | Firmicutes |
| Hydrogenoanaerobacterium | 1.39 | 6.81 | Firmicutes |
| Pyramidobacter | 1.46 | 8.84 | Synergistota |
| Victivallis | 1.34 | 14.11 | Verrucomicrobiota |
HC, healthy controls; MDD, major depressive disorder; VIP, important variables on the projection; FC, fold change, compared to HC. >1.0 and <1.0 indicated significantly lower and higher levels, respectively, in MDD patients.