Table 1.

Genetic correlation between decaffeinated coffee consumption and neuropsychiatric traits.

Phenotype 1	Phenotype 2	Rg	Rg_SE	P-Value
Coffee consumption	Alzheimer's disease	−0.0033	0.0991	0.9732
	Amyotrophic lateral sclerosis	−0.0514	0.1294	0.6914
	Neuroticism*	−0.1533	0.0387	7.27E-05
	Major depression disorder*	−0.1469	0.0447	0.0010
	Insomnia*	−0.1523	0.0451	0.0007
	Attention deficit and hyperactivity disorder	−0.0579	0.0586	0.3228
	Bipolar disorder	0.0255	0.0444	0.5657
	Lifetime cannabis use*	0.4814	0.0544	8.40E-19
	AUDIT_T*	0.3926	0.0568	4.63E-13
	AUDIT_C*	0.3981	0.0606	5.26E-11
	AUDIT_P*	0.2769	0.0637	1.36E-05
	Anorexia nervosa	−0.0020	0.0637	0.9744
	Schizophrenia	0.1002	0.0397	0.0117

Rg, genetic correlation estimate; SE, standard error; AUDIT_T, Alcohol use disorder identification test total score; AUDIT_C, alcohol consumption component of alcohol use disorder identification test item 1–3 scores; AUDIT_P, dependence and hazardous-use component of alcohol use disorder identification test item 4–10 scores.

*Correlations that were significant after Bonferroni correction (P <0.05/13 traits = 0.0038).