Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 11;9:915102. doi: 10.3389/fcvm.2022.915102

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Palm, Nijholt, Bakker and Westenbrink.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Production, distribution and yield of short-chain fatty acids (SCFAs) in different tissues. After consumption, undigested fiber reaches the colon and is fermented by microbiota. The product of this process are SCFAs. Via the portal vein SCFAs are transported to the liver and then systemically distributed. (A) Utilization of SCFAs in the colon: Butyrate is an important energy source for colonocytes. (B) Utilization of SCFAs in the liver: Propionate is mostly metabolized in the liver. (C) Relative concentrations of SCFAs in peripheral blood: Acetate has the highest peripheral concentrations. This is followed by propionate, while butyrate shows the lowest peripheral concentrations (43). Created with BioRender.com.