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. 2022 Jul 11;9:905140. doi: 10.3389/fmed.2022.905140

Table 5.

Main adverse effects during the study period among the three groups.

MX
(n = 38)
MX + SPT
(n = 37)
MX + MN
(n = 40)
Total 27 45 24
Facial hypertrichosis 4 5 5
Trichomadesis aggravating 4 4 3
Scalp pruritus 8 8 9
Increased scurf 7 6 5
Infection 0 0 1
Edema of the limbs 0 1 0
Headache 1 1 0
Palpitation 1 3 0
Postural hypotension 1 0 1
Hyperkalemia 0 1 0
Menstrual disorder 0 15 0
Urticaria 1 1 0

MX, minoxidil; SPT, spironolactone; MN, microneedling.