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. 2022 Jul 11;13:920952. doi: 10.3389/fphys.2022.920952

FIGURE 2.

FIGURE 2

Histopathological condition index (Ih) of tissues from Mytilus galloprovincialis exposed to acetylsalicylic acid (ASA): (A) gills and (B) digestive gland. The values are shown as mean ± SD (n = 3); stars represent significant differences between the treatment and control groups at the same time point. Letters are only present in the case of significant statistical differences. Different small letters indicate significant differences between time points within the same treatment group. Differences were considered significant when p < 0.05 (two-way ANOVA test/Tukey’s multiple comparisons test). ASA1 (ASA 10 μg L−1) and ASA2 (ASA 100 μg L−1). CMC, cellular and morphological changes; TA, tubular alteration; ITC, intertubular tissue changes.