TABLE 1.
B. subtilis counts in feces from outbred mice orally inoculated with 1.75 × 1011 spores in experiment 1
| Time (h) | Countsa in mouse:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1
|
2
|
3
|
4
|
5
|
||||||
| VC + SP | SP | VC + SP | SP | VC + SP | SP | VC + SP | SP | VC + SP | SP | |
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | 0 | 3.0 × 102 | 0 | 0 | 4.5 × 103 | 4.5 × 103 | 0 | 1.3 × 103 | 6.1 × 102 | 3.1 × 102 |
| 6 | 3.8 × 106 | 5.8 × 108 | 1.1 × 106 | 3.6 × 105 | 7.2 × 105 | 4.2 × 109 | 1.1 × 108 | 4.0 × 109 | 1.2 × 106 | 4.6 × 109 |
| 9 | 3.9 × 107 | 6.0 × 1010 | 3.0 × 107 | 8.3 × 1010 | 1.2 × 107 | 1.3 × 109 | 1.0 × 109 | 1.5 × 1010 | 4.3 × 107 | 4.0 × 1010 |
| 12 | 9.3 × 107 | 6.5 × 1010 | 1.5 × 107 | 4.2 × 109 | 9.0 × 107 | 3.9 × 108 | 1.9 × 107 | 6.0 × 1011 | 3.3 × 107 | 4.2 × 1011 |
| 24 | 1.1 × 109 | 9.4 × 103 | 5.0 × 104 | 1.4 × 108 | 1.0 × 107 | 6.9 × 109 | 1.3 × 105 | 9.3 × 109 | 5.3 × 104 | 7.4 × 109 |
| 48 | 3.9 × 105 | 1.7 × 105 | 6.8 × 105 | 2.3 × 104 | 9.5 × 107 | 3.7 × 1010 | 1.8 × 105 | 2.6 × 105 | 1.3 × 105 | 3.1 × 105 |
| 72 | 6.7 × 105 | 3.3 × 104 | 0 | 0 | 2.4 × 105 | 7.0 × 105 | 3.8 × 105 | 2.3 × 1 | ||
| 05 | 6.0 × 104 | 1.0 × 105 | ||||||||
| 96 | 8.7 × 102 | 1.3 × 103 | 0 | 0 | 1.4 × 103 | 1.7 × 103 | 0 | 0 | 0 | 7.2 × 102 |
| Total | 1.24 × 109 | 1.26 × 1011 | 4.68 × 107 | 8.73 × 1010 | 2.08 × 108 | 4.98 × 1010 | 1.13 × 109 | 6.28 × 1011 | 7.74 × 107 | 4.72 × 1011 |
| Ratio relative to inoculum | 0.0071 | 0.72 | 0.00027 | 0.50 | 0.0012 | 0.28 | 0.0065 | 3.59 | 0.00044 | 2.70 |
Counts of B. subtilis SC1712 obtained from fecal collection experiments. VC + SP, number of vegetative cells plus number of spores in total sample collected; SP, number of spores in sample collected. In the same experiment, feces from control groups of four mice were examined at the same time points, and no counts for B. subtilis SC1712 (VC + SP or SP) were detected (data not shown for control groups).