TABLE 1.
Basic characteristics and the clinical parameters of the subjects in Demodex group and control group.
| Parameters | Demodex group (n = 64) | Control group (n = 51) | p value | p value* |
|---|---|---|---|---|
| Age (years) | 39.0 (28.0, 57.0) | 28.98 ± 11.46 | <0.05 | — |
| (Range) | (19–78) | (8–57) | ||
| OSDI (0–100) | 22.9 (13.0, 41.7) | 7.1 (2.5, 23.2) | <0.001 | 0.002 |
| (Range) | (0–100.0) | (0–79.6) | ||
| Tear meniscus height (mm) | 0.2 (0.2, 0.2) | 0.19 ± 0.06 | 0.104 | 0.086 |
| (Range) | (0.13–0.42) | (0.06–0.33) | ||
| Tear film break-up time (seconds) | 2.3 ± 1.3 | 5.0 (2.2–5.0) | <0.001 | <0.001 |
| (Range) | (0–5) | (1–20) | ||
| Corneal fluorescein staining (0–20) | 0.0 (0.0–2.0) | 0.0 (0.0–0.0) | 0.138 | 0.587 |
| (Range) | (0–8) | (0–4) | ||
| Lid margin score (0–4) | 2.0 (2.0, 3.0) | 1.0 (0.0, 2.0) | <0.001 | <0.001 |
| (Range) | (0–4) | (0–2) | ||
| Meibum expressibility score (0–45) | 8.0 (4.0, 14.0) | 31.5 (9.5, 42.0) | <0.001 | <0.001 |
| (Range) | (0–29) | (0–45) | ||
| Meiboscore (0–6) | 3.0 (2.0–4.0) | 2.0 (1.0–3.0) | <0.001 | 0.001 |
| (Range) | (0–6) | (0–5) |
*p values adjusted for age by generalized estimating equation. OSDI, ocular surface disease index.