Table 2. Scenario-Based Affordability Assessment for Type 1 Diabetes .
Medication Therapy | Generic Name | Dose | Dosage Form | Dose of Administration/Day | Insurance Coverage (%) | Affordability Ratio |
Monotherapy | Insulin regular human | 100 IU/mL | Vial | 40 IU | 95 | 0.23 |
Insulin regular human | 100 IU/mL (3 mL) | Cartridge | 40 IU | 90 | 0.08 | |
Insulin aspart | 100 IU/mL (3 mL) | Pen | 40 IU | 90 | 0.32 | |
Insulin aspart rapid | 100 IU/mL (3 mL) | Pen | 40 IU | 90 | 0.32 | |
Insulin biphasic isophane 70+30 | 100 IU/mL (10 mL) | Vial | 40 IU | 95 | 0.02 | |
Insulin biphasic isophane | 100 IU/mL (3 mL) | Cartridge | 40 IU | 90 | 0.08 | |
Insulin isophane | 100 IU/mL (5 mL) | Vial | 40 IU | 70 | 0.27 | |
Insulin isophane (NPH) beef | 100 IU/mL | Vial | 40 IU | 70 | 1.16 | |
Insulin isophane (NPH) human | 1000 IU/10 mL | Vial | 40 IU | 95 | 0.23 | |
Insulin Isophane (NPH) Human | 100 IU/mL (3 mL) | Cartridge | 40 IU | 90 | 0.08 | |
Insulin Glargine | 300 IU/3 mL | Cartridge | 40 IU | 90 | 0.83 | |
Insulin Glargine | 300 IU/3 mL | Pen | 40 IU | 90 | 0.96 | |
Insulin Glulisine | 300 IU/3 mL | Vial | 40 IU | 70 | 2.29 | |
Insulin Lispro | 100 IU/mL | Pen | 40 IU | 0 | 70.03 | |
Insulin Detemir | 100 IU/mL | Injection | 40 IU | 70 | 3.45 | |
Combination therapy (50% basal+ 50% rapid or short acting) | NPH + Regular | 100 IU/mL | Isophane (Vial) | 0.5 IU/kg/d | 90 | 0.43 |
100 IU/mL | Regular (Vial) | 0.5 IU/kg/d | 95 | |||
NPH + Aspart | 100 IU/mL | Isophane (Vial) | 0.5 IU/kg/d | 90 | 0.67 | |
100 IU/mL | Aspart (Pen) | 0.5 IU/kg/d | 95 | |||
NPH + Glulisine | 100 IU/mL | Isophane (Vial) | 0.5 IU/kg/d | 90 | 2.36 | |
100 IU/mL | Glulisine (Pen) | 0.5 IU/kg/d | 70 | |||
Glargine + Regular | 100 IU/mL | Glargine (Pen) | 0.5 IU/kg/d | 90 | 1.11 | |
100 IU/mL | Regular (Vial) | 0.5 IU/kg/d | 95 | |||
Glargine + Aspart | 100 IU/mL | Glargine (Pen) | 0.5 IU/kg/d | 90 | 1.34 | |
100 IU/mL | Aspart (Pen) | 0.5 IU/kg/d | 95 | |||
Glargine + Glulisine | 100 IU/mL | Glargine (Pen) | 0.5 IU/kg/d | 90 | 4.79 | |
100 IU/mL | Glulisine (Pen) | 0.5 IU/kg/d | 70 |
Note: The weight 75 kg was considered in calculations.