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The role of FABP4 in tumor initiation and development. FA, fatty acid; TAMs, tumor-associated macrophages; TKIs, tyrosine kinase inhibitors. FABP4 participates in the regulation of diverse tumorigenic process, including (A) tumor growth, (B) tumor metastasis, (C) therapy resistance, (D) DNA methylation, (E) interaction between tumor cells and macrophages.
