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. 2022 Jul 11;13:948610. doi: 10.3389/fphar.2022.948610

TABLE 2.

Therapeutic targeting of FABP4 evaluated in different cancer types.

Methods Cancer Type Results References
Inhibitor Breast cancer Inhibiting growth and metastasis Uehara et al. (2014)
BMS309403
Cholangiocarcinoma Inhibiting metastasis Yang et al. (2021)
Colon cancer Inhibiting metastasis Tian et al. (2020)
Hepatocellular carcinoma Inhibiting growth and metastasis Yan et al. (2018)
Inhibiting growth and metastasis Laouirem et al. (2019)
Leukemia Inhibiting growth Yan et al. (2017)
Liver cancer Inhibiting growth and self-renewal Wang et al. (2019)
Ovarian cancer Inhibiting growth and metastasis Mukherjee et al. (2020)
Increasing sensitivity to carboplatin
Prostate cancer Inhibiting metastasis Nie et al. (2017)
Inhibitor BD62694 Ovarian cancer Inhibiting recurrence Tian et al. (2020)
siRNA Hepatocellular carcinoma Inhibiting growth and metastasis Wang et al. (2019)
Leukemia Inhibiting growth Yan et al. (2017)
Ovarian cancer Inhibiting metastasis Gharpure et al. (2018)
shRNA Triple-negative breast cancer Inhibiting metastasis Apaya et al. (2020)