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. 2022 Jul 11;13:922130. doi: 10.3389/fphar.2022.922130

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Copyright © 2022 Yao, Miao, Zhang, Zhu, Chen, Wu, Yang, Dai, Hu, Wan and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DCP ameliorated the pathological damage of intestinal and cardiac tissues in rats with SAP. (Ai,Aii): Representative images of H & E staining (× 200) on duodenum and corresponding pathological scores of rats in sham, SAP and DCP group; (Bi,Bii): Representative images of H & E staining (× 200) on colon and corresponding pathological scores of each group; (Ci,Cii): Representative images of H & E staining (× 200) on heart and corresponding pathological scores of each group. Arrows (blue, red, yellow, black) indicated edema, inflammation, necrosis, and hemorrhage respectively. The results are presented as the mean ± SEM. ***p < 0.005, ****p < 0.0001 vs. sham group, ^# p < 0.05, ^## p < 0.01 vs. SAP group; ns, p > 0.05. sham: sham operation group; SAP: Sever acute pancreatitis group; DCP: Dao-Chi powder treatment group.