TABLE 4.
Baseline characteristics among three groups categorized by tertile of neutrophil count in the cohort study
| Overall | Lowest group | Middle group | Highest group | p | |
|---|---|---|---|---|---|
| Neutrophils | |||||
| n | 2060 | 687 | 733 | 640 | |
| Age (years) | 68.93 ± 0.13 | 68.87 ± 0.24 | 68.74 ± 0.21 | 69.22 ± 0.23 | 0.327 |
| Gender (male %) | 949 (46.1%) | 292 (42.5%) | 337 (46.0%) | 320 (50.0%) b | 0.024 |
| BMI (kg/m2) | 25.39 ± 0.07 | 25.00 ± 0.13 | 25.60 ± 0.13 a | 25.57 ± 0.13 b | 0.002 |
| ALT (U/L) | 19.0 (13.6–27.8) | 18.8 (13.5–26.9) | 19.6 (13.8–29.9) | 18.9 (13.4–26.5) | 0.403 |
| TC (mmol/L) | 5.11 ± 0.02 | 5.12 ± 0.04 | 5.17 ± 0.04 | 5.02 ± 0.04 c | 0.025 |
| TG (mmol/L) | 1.40 (1.00–2.03) | 1.27 (0.94–1.86) | 1.43 (1–1.97) a | 1.54 (1.07–2.19) b | <0.001 |
| HDL (mmol/L) | 1.47 ± 0.01 | 1.53 ± 0.01 | 1.49 ± 0.01 a | 1.38 ± 0.01 b , c | <0.001 |
| LDL (mmol/L) | 2.96 ± 0.01 | 2.93 ± 0.03 | 2.99 ± 0.03 | 2.95 ± 0.03 | 0.399 |
| Cr (mol/L) | 65.74 ± 0.41 | 64.06 ± 0.76 | 65.73 ± 0.63 | 67.54 ± 0.76 b | 0.004 |
| eGFR (%) | 101.41 ± 0.56 | 103.67 ± 0.99 | 100.81 ± 0.89 a | 99.66 ± 1.03 b | 0.012 |
| FBG (mmol/L) | 8.3 (7.4–10.1) | 7.7 (7.1–9.5) | 8.0 (7.3–9.3) | 8.4 (7.5–10.9) b , c | <0.001 |
| HbA1C (%) | 7.6 (6.9–8.9) | 7.1 (6.4–8) | 7.2 (6.6–8.2) a | 7.5 (6.7–8.6) b , c | <0.001 |
| HBP (n %) | 1238 (80.1%) | 427 (76.7%) | 470 (82.2%) a | 341 (82.0%) b | 0.037 |
| NLR | |||||
| n | 2060 | 682 | 692 | 686 | |
| Age (years) | 68.93 ± 0.13 | 68.33 ± 0.23 | 68.86 ± 0.22 | 69.59 ± 0.23 b , c | 0.001 |
| Gender (male %) | 949 (46.1%) | 273 (40.0%) | 310 (44.8%) | 366 (53.4%) b , c | <0.001 |
| BMI (kg/m2) | 25.39 ± 0.07 | 25.53 ± 0.13 | 25.51 ± 0.13 | 25.13 ± 0.14 | 0.060 |
| ALT (U/L) | 19.0 (13.6–27.8) | 19.1 (14.0–29.0) | 19.7 (13.8–27.9) | 18.1 (13.0–26.0) b | 0.037 |
| TC (mmol/L) | 5.11 ± 0.02 | 5.28 ± 0.04 | 5.12 ± 0.03 a | 4.92 ± 0.03 b , c | <0.001 |
| TG (mmol/L) | 1.40 (1.00–2.03) | 1.43 (1.01–2.15) | 1.49 (1.05–2.04) | 1.31 (0.89–1.89) b , c | <0.001 |
| HDL (mmol/L) | 1.47 ± 0.01 | 1.51 ± 0.01 | 1.47 ± 0.01 a | 1.43 ± 0.01 b , c | <0.001 |
| LDL (mmol/L) | 2.96 ± 0.01 | 3.05 ± 0.03 | 2.96 ± 0.03 a | 2.87 ± 0.03 b , c | 0.001 |
| Cr (mol/L) | 65.74 ± 0.41 | 63.52 ± 0.64 | 65.29 ± 0.67 | 68.38 ± 0.82 b , c | <0.001 |
| eGFR (%) | 101.41 ± 0.56 | 103.21 ± 0.94 | 101.44 ± 0.92 | 99.58 ± 1.03 b | 0.031 |
| FBG (mmol/L) | 8.3 (7.4–10.1) | 7.9 (7.1–9.3) | 7.9 (7.2–9.5) | 8.3 (7.4–10.4) b , c | <0.001 |
| HbA1C (%) | 7.6 (6.9–8.9) | 7.2 (6.5–8.1) | 7.3 (6.6–8.3) | 7.2 (6.6–8.5) | 0.435 |
| HBP (n %) | 1238 (80.1%) | 455 (80.7%) | 424 (80.2%) | 359 (79.4%) | 0.884 |
Note: Data are mean ± SE, median (interquartile range) or n (%).
Abbreviations: ALT, alanine transaminase; BMI, body mass index; Cr, creatinine; eGFR, estimated glomerular filtration rate; FBG, fasting blood glucose; HbA1C, glycosylated hemoglobin; HBP, high blood pressure; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; NLR, neutrophil‐to‐lymphocyte ratio; TC, total cholesterol; TG, triglycerides.
a
Middle group versus lowest group, p < 0.05.
b
Highest group versus lowest group, p < 0.05.
c
Highest group versus middle group, p < 0.05.