TABLE 5.
Adjusted hazard ratios of incidence of estimated glomerular filtration rate decrease >30% in relation to tertile of neutrophil count among subjects with diabetes
| Incident case | Crude HR (95% CI) | p | Model 1 | p | Model 2 | p | |
|---|---|---|---|---|---|---|---|
| Neutrophils | |||||||
| Lowest group | 53 (7.7%) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Middle group | 60 (8.2%) | 1.038 (0.717–1.502) | 0.844 | 1.122 (0.766–1.643) | 0.554 | 1.000 (0.524–1.908) | 0.999 |
| Highest group | 78 (12.2%) | 1.547 (1.091–2.193) | 0.014 | 1.651 (1.146–2.378) | 0.007 | 2.293 (1.260–4.171) | 0.007 |
| NLR | |||||||
| Lowest group | 55 (7.8%) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | |||
| Middle group | 65 (9.4%) | 1.185 (0825–1.704) | 0.358 | 1.234 (0.850–1.793) | 0.269 | 1.358 (0.770–2.397) | 0.291 |
| Highest group | 73 (10.6%) | 1.327 (0.932–1.890) | 0.117 | 1.466 (1.013–2.122) | 0.043 | 1.415 (0.781–2.565) | 0.252 |
Note: Model 1: adjustment for gender, age, BMI; model 2: model 1 plus adjustment for HbA1C, ALT, history of HBP, total cholesterol, triglyceride, HDL‐cholesterol, LDL‐cholesterol. Abbreviations: ALT, alanine transaminase; BMI, body mass index; CI, confidence interval; HbA1C, glycosylated hemoglobin; HBP, high blood pressure; HDL, high‐density lipoprotein; HR, hazard ratio; LDL, low‐density lipoprotein; NLR, neutrophil‐to‐lymphocyte ratio.