Table 3.
Univariate and multivariate Cox regression analysis for overall survival (n = 215).
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| Age (years) | >65/⩽65 | 1.158 (0.703-1.907) | 0.565 | / | / |
| Sex | Male/female | 2.204 (1.263-3.847) | 0.005 | 1.462 (0.806-2.650) | 0.211 |
| CEA (ng/mL) | >5/⩽5 | 2.821 (1.696-4.694) | <0.000 | 1.580 (0.911-2.739) | 0.103 |
| CA199 (U/mL) | >37/⩽37 | 3.864 (2.337-6.391) | <0.000 | 2.025 (1.172-3.500) | 0.011 |
| Tumor location | Left-side/right-side | 0.777 (0.465-1.298) | 0.336 | / | / |
| Tumor size (cm) | >5.0/⩽5.0 | 2.463 (1.396-4.345) | 0.002 | 2.560 (1.340-4.891) | 0.004 |
| Histological type | Mucinous/adenocarcinoma | 1.002 (0.457-2.199) | 0.996 | / | / |
| Primary differentiation | Poor/well | 1.919 (1.167-3.157) | 0.01 | 1.648 (0.976-2.783) | 0.061 |
| T-stage | T3-4/T1-2 | 5.106 (1.854-14.062 | 0.002 | 1.257 (0.405-3.900) | 0.692 |
| N-stage | N1-2/N0 | 2.966 (1.766-4.982) | <0.000 | 1.644 (0.939-2.880) | 0.082 |
| M-stage | M1/M0 | 7.874 (4.754-13.053) | <0.000 | 4.798 (2.722-8.455) | <0.000 |
| YTHDC2 level | Low/high | 1.812 (1.102-2.979) | 0.019 | 1.959 (1.157-3.315) | 0.012 |