Table 1.
Univariable and adjusted analysis of the association of depression with CDAI and SDAI remission.
| Univariable analysis | CDAI-remission | SDAI-remission | ||||
|---|---|---|---|---|---|---|
| Events/ patients | HR [95% CI] | p-value | Events/ patients | HR [95% CI] | p-value | |
| Comorbid depression | ||||||
| No | 1677/4989 | 1 | 1396/4982 | 1 | ||
| Yes | 103/512 | 0.55 [0.45–0.67] | <0.001 | 78/510 | 0.50 [0.40–0.63] | <0.001 |
| Adjusted analysis | CDAI-remission | SDAI-remission | ||||
| Events/ patients | HR [95% CI] | p-value | Events/ patients | HR [95% CI] | p-value | |
| Comorbid depression | ||||||
| No | 1677/4989 | 1 | 1396/4982 | 1 | ||
| Yes | 103/512 | 0.62 [0.48–0.80] | <0.001 | 78/510 | 0.59 [0.44–0.79] | <0.001 |
CDAI, clinical disease activity index; CI, confidence interval; HR, hazard ratio; SDAI, simple disease activity index.
Adjustment variables: age, weight, sex, race, baseline disease activity, antidepressant use, corticosteroids, disease duration and number of previous DMARDs.