Table 3.
Univariable and adjusted analysis of the association of anxiety with CDAI and SDAI remission.
| Univariable analysis | CDAI-remission | SDAI-remission | ||||
|---|---|---|---|---|---|---|
| Events/ patients | HR [95% CI] | p-value | Events/ patients | HR [95% CI] | p-value | |
| Comorbid anxiety | ||||||
| No | 1725/5264 | 1 | 1424/5257 | 1 | ||
| Yes | 55/236 | 0.68 [0.52–0.89] | 0.005 | 50/235 | 0.78 [0.59–1.03] | 0.084 |
| Adjusted analysis | CDAI-remission | SDAI-remission | ||||
| Events/ patients | HR [95% CI] | p-value | Events/ patients | HR [95% CI] | p-value | |
| Comorbid anxiety | ||||||
| No | 1725/5264 | 1 | 1424/5257 | 1 | ||
| Yes | 55/236 | 0.80 [0.60–1.06] | 0.114 | 50/235 | 0.93 [0.69–1.25] | 0.647 |
CDAI, clinical disease activity index; CI, confidence interval; DMARD, disease-modifying antirheumatic drugs; HR, hazard ratio; SDAI, simple disease activity index.
Adjustment variables: age, weight, sex, race, baseline disease activity, antidepressant use, corticosteroids, disease duration and number of previous DMARDs.