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. 2022 Jul 11;10:886316. doi: 10.3389/fcell.2022.886316

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Copyright © 2022 Fallatah, Cui, Di Pietro, Carter, Pounder, Dorninger, Pifl, Moser, Berger and Braverman.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The hyperactivity behavior of Pex7 deficient mice in the open field environment. Pex7 deficient mice showed significant increase in activity levels measured by distance traveled (A) and activity time (B) at different ages in comparison to controls (Pex7 ^WT/WT and Pex7 ^WT/hypo). Representative images of track blots recorded during the open field test of Pex7 deficient mice and their littermate controls (C). Bars represent group means ± SD. ns: nonsignificant, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (n = 12–36 per genotype).