Table 2.

Infectious Disease Physician Preferences in Antifungal Therapy Based on Clinical Scenario

Clinical Situation	Itraconazole	Voriconazole	Posaconazole	Isavuconazole	Fluconazole	AmB	No Treatment	Not Answered
Mild-moderate acute pulmonary histoplasmosis with symptoms lasting >1 mo	189 (75)	3 (1)	2 (<1)	0 (0)	2 (<1)	9 (4)	47 (19)	1 (<1)
Mild-moderate progressive disseminated histoplasmosis (outpatient presentation)	189 (75)	3 (1)	2 (<1)	0 (0)	1 (<1)	22 (9)	35 (14)	1 (<1)
Step-down therapy for disseminated histoplasmosis without CNS involvement after AmB induction	232 (92)	8 (3)	9 (4)	0 (0)	3 (1)	NA	NA	1 (<1)
Step-down therapy for disseminated histoplasmosis with CNS involvement after AmB induction	145 (57)	48 (19)	12 (5)	9 (4)	20 (8)	17 (7)	NA	2 (<1)

Data are presented as No. (%) of respondents (n = 253).

Abbreviations: AmB, amphotericin B; CNS central nervous system; NA, not applicable.