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. 2022 Jul 8;7(13):e152738. doi: 10.1172/jci.insight.152738

Figure 2. HIV-1 and cART induce M2-like macrophages in the liver of hu-mice.

Figure 2

Assessment of human immune cells infiltrated in livers of treated NRG-hu mice collected at 12–13 wpi. (A) H&E, SR, and immunofluorescence staining for human CD68 (red), MerTK (green), and nuclei (blue) in the livers of hu-mice (original magnification, ×20). (B) RT-qPCR analysis of human MerTK mRNA in the liver. Data were normalized with mouse Gapdh. Bars in the scatter plots represent the median value. Statistical analysis was performed with 1-way ANOVA and Turkey’s post hoc test. *P < 0.05.