Skip to main content
. 2022 Jul 8;7(13):e149825. doi: 10.1172/jci.insight.149825

Figure 2. Reduced inflammation of IRAK1KD mice in the TMPD peritonitis model.

Figure 2

(A) ISG expression by peritoneal exudate cells, 1 representative of 2 independent experiments, means ± SEM, unpaired t test. (B) Total counts of peritoneal monocytes and neutrophils, (C and D) CXCL1, CXCL2, CXCL5, IL-1α, and IL-1β in peritoneal lavages. (B–D) Combined from 2 independent experiments, means ± SD, unpaired t test. (E) IL-1β secretion following LPS/TMPD stimulation of peritoneal macrophages in vitro. Means ± SD, 1 representative of 2 independent experiments. Two-way ANOVA, Holm-Šidák multiple comparison. Data points in all panels represent individual mice. *P < 0.05, **P < 0.01, ****P < 0.0001.