Table 4.

TEAEs (≥2 patients) within 24 hours after nitroglycerin administration on 6 profile days ^a

Primary system organ class b	Vericiguat + nitroglycerin (n = 24)	Placebo + nitroglycerin (n = 12)
Number of patients (%) with at least one TEAE	16 (66.7)	8 (66.7)
Hypotension	7 (29.2)	2 (16.7)
Headache	4 (16.7)	1 (8.3)
Nausea	2 (8.3)	2 (16.7)
Fatigue	2 (8.3)	1 (8.3)
Amylase increased	1 (4.2)	2 (16.7)
Lipase increased	0	2 (16.7)

MedDRA, Medical Dictionary for Regulatory Activities; TEAE, treatment‐emergent adverse event.

^a Six profile days = 3 trough and 3 peak days for the vericiguat + nitroglycerin group (vericiguat 2.5 mg, 5 mg, and 10 mg) and placebo + nitroglycerin group.

^b Preferred term MedDRA version 19.0.