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. Author manuscript; available in PMC: 2022 Jul 25.
Published in final edited form as: Eur Urol Oncol. 2020 Oct 21;4(2):227–234. doi: 10.1016/j.euo.2020.09.004

Table 4 –

Total number of biopsies performed and avoided if performing biopsy only for a positive change in MRI (PRECISE scores ≥4) at 2-yr follow-up.

Biopsy threshold Progression endpoints Total biopsies, N Total progressed, N (%) Performed biopsies, N Avoided biopsies, N Missed progression in avoided biopsies, N (%)

Positive change in MRI GG1–>GG2 194 55 (28.4) 85 109 24 (22)
GG1–>GG3 194 16 (8.25) 85 109 4 (3.7)
GG2–>GG3 78 26 (33.3) 38 40 9 (22.5)

GG = Gleason grade group; MRI = magnetic resonance imaging; PRECISE = Prostate Cancer Radiologic Estimation of Change in Sequential Evaluation.