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. 2022 Mar 7;42(5):984–994. doi: 10.1111/liv.15209

TABLE 6.

Predictors of non‐adherence to lifestyle changes (multinomial weighted logistic regression a , crude odds ratios [OR] and adjusted odds ratios [AOR] and their 95% confidence intervals [95% CI] N = 1411)

Characteristics Lifestyle changes Multivariable analysis b
Poor versus good adherence Poor versus good adherence
Good adherence (51.6%) Poor adherence (34.4%) Not a concerned (14.0%) OR 95% CI p‐value AOR 95% CI p‐value
% % %
Gender
Male 59.1 32.5 8.40 Ref Ref
Female 42.8 36.6 20.6 1.55 1.17 2.06 .002 1.44 1.02 2.01 .040
Countries
UK 43.5 27.8 28.7 Ref Ref
Germany 41.9 44.1 14.0 1.65 1.05 2.59 .031 1.32 0.75 2.33 .337
France 37.2 46.2 16.6 1.95 1.18 3.22 .010 1.90 1.04 3.50 .037
Canada 63.4 34.1 2.50 0.84 0.50 1.40 .505 0.70 0.39 1.29 .258
Italy 63.6 27.3 9.10 0.67 0.40 1.14 .142 0.49 0.27 0.92 .027
Spain 62.9 27.2 9.90 0.68 0.40 1.15 .148 0.88 0.49 1.59 .681
BMI
<20 59.2 27.8 13.0 Ref Ref
[20–25[ 24.8 46.0 29.2 3.96 0.87 63.4 .330 2.39 0.10 62.5 .587
[25–30[ 48.9 40.1 11.0 1.75 0.77 3.97 .180 0.96 0.34 2.75 .944
[30–35[ 33.7 47.6 18.7 3.00 1.80 5.00 <.001 3.12 1.74 5.60 <.001
≥35 28.6 55.4 16.0 4.14 2.74 6.23 <.001 2.98 1.82 4.87 <.001
Fibrosis score
Known 66.8 26.2 7.0 Ref Ref
Unknown 41.2 40.0 18.8 2.48 1.84 3.33 <.001 1.70 1.14 2.41 .008
Nurse support c
Poor 37.9 43.2 18.9 Ref Ref
Good 71.3 22.9 5.8 0.28 0.20 0.39 <.001 0.37 0.25 0.54 <.001

Abbreviations: BMI, body mass index; ref, reference category.

a

Only the results comparing poor adherence versus good adherence to lifestyle changes were reported as the comparison of ‘not concerned’ versus good adherence was meaningless.

b

All analyses are weighted with weight proportional to the age‐gender distribution of a population with non‐alcoholic fatty liver disease/non‐alcoholic steatohepatitis, in order to control for selection bias of participants and allow for inter‐country comparisons.

c

Nurses and other health staff other than physicians for lifestyle changes; poor = no+low, good = moderate+high.