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. 2022 Mar 3;29(5):1435–1445. doi: 10.1111/ene.15261

TABLE 6.

Differences in adjusted mean cervical spinal cord gray matter areas between post‐polio syndrome patients with upper limb involvement during the acute infection and healthy control persons and between patients without upper limb involvement during the acute infection and healthy control persons

GM area (mm2) at intervertebral disc level Group Estimate a /SE 95% CI for the estimate a Adjusted b mean GM area (mm2)/SE

p Value

First rater

p Value

Additional rater

C2/C3 With UL involvement −1.14/0.64 (−2.45, 0.17) 14.38/0.52 0.086 0.104
Without UL involvement −0.91/0.74 (−2.42, 0.59) 14.60/0.63 0.226 0.305
Controls 15.51/0.40
C3/C4 With UL involvement −3.71/0.72 (−5.16, −2.25) 15.61/0.58 <0.001 <0.001
Without UL involvement −2.02/0.82 (−3.70, −0.35) 17.29/0.69 0.019 0.078
Controls 19.32/0.44
C4/C5 With UL involvement −4.07/0.66 (−5.40, −2.74) 16.65/0.53 <0.001 <0.001
Without UL involvement −2.19/0.73 (−3.68, −0.70) 18.53/0.62 0.005 0.008
Controls 20.71/0.39
C5/C6 With UL involvement −3.69/1.02 (−5.78, −1.62) 16.40/0.83 0.001 0.002
Without UL involvement −2.22/1.15 (−4.55, 0.11) 17.88/0.96 0.061 0.218
Controls 20.10/0.61
C6/C7 With UL involvement −2.04/1.06 (−4.18, 0.11) 15.49/0.86 0.063 0.028
Without UL involvement −1.38/1.18 (−3.78, 1.02) 16.15/0.99 0.250 0.150
Controls 17.53/0.63

The values in bold type denote significant p‐values.

Abbreviations: CI, confidence interval; GM, gray matter; SE, standard error; UL, upper limb.

a

The estimate equals the difference between a level and the reference level (controls),

b

Means are least‐square means with adjustment for age and sex using linear regression.