TABLE 7.

ANOVA analysis of AUC of midazolam and α‐hydroxymidazolam following treatment with BAY 2433334 in Part C

			AUC ratio day 1/day−1		AUC ratio day 10/day−1
Treatment	Analyte	n	Point estimate geometric LS means (geometric 90% CI)	n	Point estimate geometric LS means (geometric 90% CI)
BAY 2433334 25 mg OD + Midazolam	Midazolam	24	1.0415 (0.9659–1.1230)	24	1.0630 (0.9859–1.1461)
	α‐Hydroxymidazolam	22	1.0650 (0.9661–1.1741)	24	1.0560 (0.9595–1.1622)
BAY 2433334 75 mg OD + Midazolam	Midazolam	24	1.0451 (0.9785–1.1164)	22	1.1736 (1.0963–1.2564)
	α‐Hydroxymidazolam	24	0.9856 (0.9206–1.0551)	20	0.9864 (0.9169–1.0612)

ANOVA, analysis of variance; AUC, area under the plasma concentration–time curve; CI, confidence interval; LS, least squares; OD, once daily.