Table 3.

Univariate Cox proportional hazard analyses for OS in EOC patients from the SOC and DCVAC arms in SOV01.

SOC arm				DCVAC arm
Variable	HR (95% CI)	p-value		Variable	HR (95% CI)	p-value
IL10	2.1 (1.3–3.5)	0.005		NCR1	1.9 (1.2–3)	0.007
IL15RA	5.4 (1.6–1.8)	0.005		GZMA	1.8 (1.1–2.9)	0.012
CD8A	1.6 (1.1–2.2)	0.009		IL4	2.4 (1.2–4.7)	0.015
SMAD3	5.1 (1.3–2)	0.019		CD4	2.4 (1.2–5)	0.017
TGFB1	3.6 (1.2–11)	0.023		CD3E	2.1 (1.1–4.2)	0.028
HLA-DOB	0.6 (0.3–0.1)	0.033		HLA-DOB	1.6 (1–2.6)	0.037
NECTIN2	2.6 (1.1–6.4)	0.033		GZMB	1.7 (1–2.9)	0.044
IL6	0.6 (0.4–0.1)	0.046		FOXP3	2 (1–3.9)	0.047

PFS = progression-free survival; EOC = epithelial ovarian cancer; SOC = standard of care chemotherapy; DCVAC, dendritic cell-based vaccination; HR = hazard ratio; CI = confidence interval