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Electrocardiographic recordings. Two-channel cardiac rhythm recordings are shown in the WT, Pdgfra-Cre, Pdgfra-Cre:LmnaW/F, and Pdgfra-Cre:LmnaF/F mice. The Pdgfra-Cre:LmnaW/F mice showed second and third-degree atrioventricular blocks after one year of age (third set of panels). The Pdgfra-Cre:LmnaF/F mice exhibited runs of wide complex and narrow complex tachycardia episodes at 6 weeks of age (the lower panels).
