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. 2022 Jul 18;45(8):352–365. doi: 10.1097/COC.0000000000000932

TABLE 3.

Oncotherapeutic Agents Approved Since 2018 With No Mention of Hepatic Adverse Events on the Product Label

Drug (Ref) Drug Class/Therapeutic Use
Tumorocentric drugs
 Enfortumab vedotin-ejfv76 Nectin-4–directed antibody-drug conjugate/urothelial cancer
 Apalutamide77 Androgen receptor inhibitor/prostate cancer
 Selinexor78 Nuclear export inhibitor/RRMM
Immuno-oncology drugs
 Daratumumab + hyaluronidase79 CD38-directed cytolytic antibody + endoglycosidase/MM
 Isatuximab-irfc80 CD38-directed cytolytic antibody/RRMM
 Mogamulizumab-kpkc81 CCR4-directed monoclonal antibody/relapsed or refractory mycosis fungoides or Sézary syndrome after ≥1 prior systemic therapy

MM indicates multiple myeloma; RR, relapsed or refractory.