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. 2022 Jun 27;11(7):863. doi: 10.3390/antibiotics11070863

Table 1.

SSI rates in children and neonates.

Study Type of Study (N of Patients) Study Population SSI Rate Type of Surgery
Murray, 2014 [26] Single-center, retrospective (470) 0–1 y.o., postoperative 3.4% (6.8 in neonates) Cardiac surgery
Lejus, 2013 [39] Single-center, retrospective (286) neonates, postoperative 3.8% Non-specified
Zingg, 2017 [19] Multicenter, retrospective (17,273) 0–18 y.o., all patients 0.18% Non-specified
Boomer, 2014 [30] Single-center, retrospective (1388) 0–18 y.o., postoperative 5.1% Appendicectomy
Katayanagi, 2015 [25] Single-center, retrospective (174) 0–15 y.o., postoperative 17% and 6.9% ** (superficial SSI)
13% and 3% ** (space SSI)
Cardiac surgery
Clements, 2016 [37] Single-center, retrospective (165) neonates, postoperative 11.7% Non-specified
Prasad, 2016 [38] Multicenter, retrospective (902) neonates, postoperative 4.46% Non-specified
Kulaylat, 2018 [18] Multicenter, retrospective (129,849) 0–18 y.o., postoperative 0.9% Non-specified
Blackwood *, 2017 [20] Multicenter, retrospective (66,671) 2–18 y.o., postoperative 2% Non-specified
Blackwood *, 2017 [20] Multicenter, retrospective 2–18 y.o., postoperative 3.6% Paediatric general surgery
Blackwood *, 2017 [20] Multicenter, retrospective 2–18 y.o., postoperative 2.5% Cardiothoracic surgery
Blackwood *, 2017 [20] Multicenter, retrospective 2–18 y.o., postoperative 2.4% Paediatric neurosurgery
Inoue, 2018 [35] Single-center, retrospective (181) neonates, postoperative 8.8% Non-specified
Bartz-Kurycki, 2018 [36] Multicenter, retrospective (3589) neonates, postoperative 4% Non-specified
Malik, 2019 [34] Multicenter, retrospective (1891) 2–18 y.o., postoperative 4.2% Posterior spinal fusion
Li, 2019 [17] Single-center, retrospective (18,314) 0–18 y.o., postoperative 0.9% Non-specified
Canadian Nosocomial Infection Surveillance Program, 2020 [22] Multicenter, retrospective (266) 0–18 y.o., postoperative 3.3% Paediatric neurosurgery
Canadian Nosocomial Infection Surveillance Program, 2020 [22] Multicenter, retrospective 0–18 y.o., postoperative 4.1% Cardiac surgery
Woodward, 2020 [23] Multicenter, retrospective (807) 0–18 y.o., postoperative 2.4% (superficial SSI) Cardiac surgery
Shibamura-Fujiogi, 2020 [29] Single-center, retrospective (621) 0–18 y.o., postoperative 6.3% Intestinal surgery
Pough, 2020 [27] Single-center, retrospective (192) 0–18 y.o., postoperative 6% Colo-rectal surgery
Tipper, 2019 [32] Single-center, prospective (355) 2.5–17.9 y.o., postoperative 1.9% and 2.5% (idiopathic and neuromuscular scoliosis, respectively) Spinal surgery
Furdock, 2020 [33] Multicenter, retrospective (111) 8–20 y.o., postoperative 6.3% Spinal surgery

* This study both reported overall SSI rates and subspecialty-specific SSI rates. ** Before and after the implementation of new prevention strategies.