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. 2022 Jun 22;11(7):1218. doi: 10.3390/antiox11071218

Figure 2.

Figure 2

Effect of dim light at night on hippocampal neurons in mice. (A) NeuN immunohistochemical staining in the CA1 and CA3 regions of the hippocampus in the different groups. Bar =50 μm. (B) The NeuN-positive cells in the hippocampal CA1 region (n = 9). (C) The NeuN-positive cells in the hippocampal CA3 region (n = 9). (D) Relative protein levels of BCL2 in the hippocampus (n = 3). (E) Relative protein levels of BAX in the hippocampus (n = 3). (F) Relative protein levels of cleaved-caspase3 in the hippocampus (n = 3). (G) The ratio of BCL-2 and BAX protein expression levels (n = 3). (H) The mRNA levels of Bdnf (n = 4). (I) The mRNA levels of Psd95 (n = 4). (J) The mRNA levels of Snap25 (n = 4). (K) The mRNA levels of Sirt1 (n = 4). (L) The mRNA levels of Dcx (n = 4). Differences were assessed using one-way ANOVA. The result represents the mean ± standard error of the mean. Values not sharing a common superscript letter (a,b) differ significantly at p < 0.05; those with the same letter (a,b) do not differ significantly (p ≥ 0.05). Ctrl: control group, dLAN-WL: dim white light at night group, dLAN-BL: dim blue light at night group.