Fig. 2.

Results of genome‐wide association studies of high‐density lipoprotein (HDL)‐mediated cholesterol efflux capacity (CEC) and HDL cholesterol (HDL‐C). Genome‐wide association studies of HDL‐CEC and HDL‐C were performed in five Finnish cohorts (total n = 20,372). Each dot represents a single single nucleotide polymorphism (SNP); 500‐kb regions flanking the lead SNPs in the associated loci are highlighted. The level of genome‐wide significance (p < 5 × 10^–8) is indicated by a red dashed line. Altogether two and 13 genome‐wide significant loci were detected for HDL‐CEC and HDL‐C, respectively.