Generic
|
ARE |
Antioxidant-response element |
E |
Extract |
EC
50
|
Half maximal effective concentration |
Fx |
Fucoxanthin |
CHE |
Convectional heat extraction |
HPLC-DAD |
High Performance Liquid Chromatography - Photodiode array detector |
AS dw |
Algae sample dry weight |
MAE |
Mean absolute error |
PDB |
Protein Data Bank |
RMSE |
Root mean squared error |
ROS |
Reactive oxygen species |
SMILES |
Simplified Molecular Input Line Entry |
S
|
Solvent concentration |
t
|
Time |
T
|
Temperature |
UV |
Ultraviolet |
Compounds
|
AAPH |
2,2′-azobis-2-amidinopropane: RN = NR |
ABTS |
2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid |
ALA |
Alanine |
DMSO |
Dimethyl sulfoxide |
DNA |
Deoxyribonucleic acid |
DPPH |
2,2-diphenyl-1-picrylhydrazyl |
HCl |
Hydrochloric acid |
LEU |
Leucine |
K2S2O8
|
Potassium persulfate |
THR |
Threonine |
TYR |
Tyrosine |
Neuroprotective activity
|
I/R |
Ischemic/reperfusion |
MCAO |
Middle cerebral artery occlusion |
MHB |
Mueller Hinton Broth |
Nrf2 |
Nuclear factor erythroid 2-related factor 2 |
Nrf2-ARE |
Nuclear factor erythroid 2-related factor 2 antioxidant-response element |
OGD/R |
Oxygen-glucose deprivation and reoxygenation |
TBI |
Traumatic brain injury |
Proteins
|
AChE |
Acetylcholinesterase |
BuChE |
Butyrylcholinesterase |
DR |
Dihydrofolate reductase |
GY |
Gyrase |
KS |
Beta-ketoacyl-(acyl carrier protein) synthase I |
In silico studies
|
ADME |
Absorption, distribution, metabolism and excretion |
BBB |
Blood–brain barrier permeability |
CYP |
Cytochrome P interaction |
GI |
Gastrointestinal absorption |
Kp
|
Permeability coefficient |
Pgp |
Glycoprotein-P interaction |
RMSD |
Root-mean-square deviation |