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. 2022 Jun 29;11(7):1296. doi: 10.3390/antiox11071296
Generic
ARE Antioxidant-response element
E Extract
EC 50 Half maximal effective concentration
Fx Fucoxanthin
CHE Convectional heat extraction
HPLC-DAD High Performance Liquid Chromatography - Photodiode array detector
AS dw Algae sample dry weight
MAE Mean absolute error
PDB Protein Data Bank
RMSE Root mean squared error
ROS Reactive oxygen species
SMILES Simplified Molecular Input Line Entry
S Solvent concentration
t Time
T Temperature
UV Ultraviolet
Compounds
AAPH 2,2′-azobis-2-amidinopropane: RN = NR
ABTS 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid
ALA Alanine
DMSO Dimethyl sulfoxide
DNA Deoxyribonucleic acid
DPPH 2,2-diphenyl-1-picrylhydrazyl
HCl Hydrochloric acid
LEU Leucine
K2S2O8 Potassium persulfate
THR Threonine
TYR Tyrosine
Neuroprotective activity
I/R Ischemic/reperfusion
MCAO Middle cerebral artery occlusion
MHB Mueller Hinton Broth
Nrf2 Nuclear factor erythroid 2-related factor 2
Nrf2-ARE Nuclear factor erythroid 2-related factor 2 antioxidant-response element
OGD/R Oxygen-glucose deprivation and reoxygenation
TBI Traumatic brain injury
Proteins
AChE Acetylcholinesterase
BuChE Butyrylcholinesterase
DR Dihydrofolate reductase
GY Gyrase
KS Beta-ketoacyl-(acyl carrier protein) synthase I
In silico studies
ADME Absorption, distribution, metabolism and excretion
BBB Blood–brain barrier permeability
CYP Cytochrome P interaction
GI Gastrointestinal absorption
Kp Permeability coefficient
Pgp Glycoprotein-P interaction
RMSD Root-mean-square deviation