Table 2.
Co-infection status and treatment response in 25 patients on HDDCT.
| Response to Therapy |
1 Course of HDDCT |
2 Courses of HDDCT | 3 Courses of HDD CT |
LOI 1–4 yrs. |
LOI 5–9 yrs. |
LOI 10–20 yrs. | LOI 20+ yrs. | Age < 50 | Age > 50 | Bm | Bd | Bab FISH+ | E | A | BartAB+ | VEGF+ | Bart PCR+ |
Bart FISH+ | 0 Co-inf | 1 Co-inf | 2 Co-inf | 3 Co-inf |
EM+ | EM− |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Remission | 6 | 1 | 1 | 0 | 2 | 3 | 3 | 4 | 4 | 3 | 2 | 3 | 1 | 1 | 3 | 1 | 0 | 2 | 0 | 3 | 4 | 1 | 3 | 5 |
| Improved 10–20% |
6 | 1 | 2 | 0 | 3 | 2 | 4 | 6 | 3 | 2 | 2 | 4 | 4 | 0 | 6 | 2 | 1 | 2 | 0 | 2 | 3 | 4 | 3 | 6 |
| Improved 21–30% |
0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
| Improved >30% | 2 | 0 | 1 | 0 | 0 | 3 | 0 | 1 | 2 | 0 | 1 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 2 |
| No change | 4 | 0 | 0 | 0 | 0 | 1 | 3 | 1 | 3 | 3 | 0 | 2 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 4 |
Abbreviations: Length of illness (LOI); Years (yrs.); Babesia microti (Bm); Babesia duncani (Bd); Babesia florescent in situ hybridization (Bab FISH); Ehrlichia (E); Anaplasma (A); Bartonella antibody (Bart AB); vascular endothelial growth factor (VEGF); Bartonella polymerase chain reaction (Bart PCR); Bartonella florescent in situ hybridization (Bart FISH); co-infections (Co-inf). erythema migrans (EM).