Table 1.
Genotypic characteristics of CRAB isolates and their MICs for antibiotics used in time-kill assays. Interpretations of MICs are provided in parentheses.
| Isolate | Sequence Type | β-Lactamase * | MIC (mg/L) | ||||
|---|---|---|---|---|---|---|---|
| Polymyxin B | Meropenem | Minocycline | Ampicillin/ Sulbactam |
Rifampin | |||
| AR-276 | ST530 | bla ADC-130 | 1 (I) | 8 (R) | 0.125 (S) | 8/4 (S) | 8 |
| AR-279 | ST2 | blaTEM-1D, blaOXA-23, blaOXA-66, blaADC-162 | 0.5 (I) | 64 (R) | 4 (S) | 64/32 (R) | 32 |
| AR-285 | ST79 | blaTEM-1B, blaOXA-65, blaADC-215 | 0.5 (I) | 256 (R) | 0.125 (S) | 32/16 (R) | 4 |
| AR-313 | ST1 | blaTEM-1D, blaOXA-23, blaOXA-69, blaADC-176 | 0.5 (I) | 16 (R) | 4 (S) | 64/32 (R) | 4 |
MIC interpretations according to CLSI-ED32 (2022). * Bold β-Lactamase genes have been shown to hydrolyze carbapenems.