Figure 5.

Score plot (A) and loading plot (B) of PCA revealed the distinguished profile of the intact neutral lipids in LDs from oxHDL-supplemented HK-2 cells. (C) Heatmap of the most significant varied LD phospholipid species among different oxHDL-induced cells. (D) Bubble plots of LD PC and LD PE profile changes in the cells supplemented using oxHDL with different preparation times. The color (ranging from red to cyan) and the bubble scales represent the degree of the difference, calculated as log₂ (change fold of 2−4 h groups to 0−0.5 h groups). (E) PC/PE ratio of LDs in different groups, * p < 0.05, ** p < 0.01 vs. 0 h group, calculated by one-way ANOVA with Dunnett’s post hoc test.