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The distributions of Index that is the proportion of cavity residues with high confidence (pLDDT > 90). AF_cavity: cavities detected from AlphaFold predicted protein structures; Subset_1: cavities from proteins that have known 3D structures in our hrefPDB dataset; Subset_2: the remaining cavities after removing Subset_1 from AF_cavity. The distributions of all cavities (blue) and cavities with strong druggability (orange) in each dataset are displayed respectively.
