Table 2.

Cellular pathways involved in ZFP regulation in the nervous system.

Zinc Finger Protein	Function	Reference
CIZ1	Maintain the balance of LPO and GSH and participate in NF-κB, oxidative stress, vascular dysfunction, inflammation, and cell death Affect the cell cycle and related DNA repair pathways of post-mitotic neurons It is involved in regulating ARCD, motor decline, and age-related neurological diseases	[174,175,176]
Unkempt	Regulation of retinal photoreceptor differentiation in the mTOR downstream pathway Regulate the cell cycle of neural progenitor cells Affect cognitive flexibility and participate in the regulation of cognitive impairment diseases	[178,179,181,188,189]
ZFP804A	It affects the expression of genes such as cell adhesion, mitosis, neural differentiation, and inflammatory response, and participates in neuronal migration, axon growth, and synaptic formation Damage dendritic morphology and participate in the regulation of dendritic synaptic defects Affect the spinal cord density or axon dendritic state of the cerebral cortex and hippocampus Regulate people’s language, reading, and cognitive abilities, and participate in the regulation of cognitive impairment-related diseases	[193,195,200,201,202]