Table 4.
Association of the content of CD68, PU.1, CD163, CD66b, CD56, CD20, CD3, CD8, FoxP3 positive cells in the stroma with the histological type of tumor and stage of the disease (median 25–75%).
| Histology | Stage | ||||||
|---|---|---|---|---|---|---|---|
| ccRCC | papRCC | chRCC | p | I–II | III–IV | p | |
| CD68 | 18.0 (8.6–22.4) | 11.4 (5.8–15.4) | 9.5 (4.5–13.4) | 0.041 * | 10.8 (6.1–16.8) | 18.5 (4.9–22.5) | 0.230 |
| PU.1 | 17.4 (7.2–25.8) | 20.2 (7.8–29.8) | 7.0 (3.6–14.6) | 0.054 | 10.8 (5.3–24.7) | 17.3 (6.7–27.7) | 0.268 |
| CD163 | 11.6 (6.2–15.8) | 8.4 (5.6–11.0) | 3.6 (2.7–6.8) | 0.043 * | 6.7 (3.3–11.5) | 9.9 (3.8–15.7) | 0.203 |
| CD66b | 2.6 (1.4–5.6) | 4.8 (2.0–8.0) | 1.7 (1.2–3.0) | 0.019 * | 2.5 (1.2–5.2) | 2.3 (1.6–5.0) | 0.980 |
| CD56 | 1.8 (0.6–11.8) | 1.2 (0.8–3.6) | 1.7 (0.7–9.5) | 0.611 | 1.6 (0.7–7.3) | 1.5 (0.9–9.85) | 0.788 |
| CD20 | 2.6 (1.0–5.8) | 3.2 (1.4–5.4) | 2.7 (0.6–6.5) | 0.603 | 3.0 (0.9–6.0) | 3.6 (0.9–4.9) | 0.957 |
| CD3 | 16.8 (4.2–32.8) | 7.2 (5.4–12.4) | 1.8 (1.1–6.1) | 0.001 * | 5.5 (1.9–12.6) | 9.7 (1.8–34.3) | 0.152 |
| CD8 | 7.4 (1.8–20.0) | 7.0 (2.0–10.6) | 2.4 (0.6–3.6) | 0.002 * | 3.5 (1.5–7.7) | 8.1 (1.2–22.75) | 0.141 |
| FoxP3 | 0.2 (0.0–0.6) | 0.4 (0.0–0.8) | 0.4 (0.0–0.8) | 0.383 | 0.4 (0.0–0.8) | 0.2 (0.0–0.6) | 0.336 |
* indicates p-values of statistically significant differences.