Figure 1.

Circulating concentrations of cytokines. Serum fractalkine (A), interferon (IFN)γ (B), interleukin (IL)2 (C), IL-6 (D), tumor necrosis factor (TNF)α (E), IL-4 (F), IL-10 (G), adiponectin (H) and irisin (I) levels in control rats (C), pair-fed rats (PF) and rats receiving chronic intracerebroventricular leptin infusion (L). Data are presented as means ± SEM. NS, non-significant. * p < 0.05, ** p < 0.01, *** p < 0.001; one-way ANOVA followed by Bonferroni’s test. Dots represent the individual data.