Figure 8.

Representative immunostaining of the KLK6 in paraffin sections of colonic tissues from patients with adenocarcinoma. (A) KLK6 immunoreactivity is absent in ‘normal-appearing’ colonic mucosa very distant (more than 10 cm) from a colon adenocarcinoma (B) Immunostaining for KLK6 in the dysplastic colonic mucosa from the same patient as in (A) is seen. (C–F) Moderate to strong positive immunoreactivity in the adenocarcinomas of four different patients. KLK6 immunoreactivity appeared to be distinguishable into a predominantly apical/cytoplasmic pattern (arrows). Bar = 100 µm (A–F), 10 µm (D).