Table 1.

Estimation of KLK6 expression in colon carcinoma epithelial cells.

Cases	Age	Gender	Tumor Site	Histological Type	Tumors Stage	Differentiation Grade	Percent of Stained Cells	Staining Intensity	Scores
1	77	F	Cecum	Adenocarcinoma	T3N0 MX	3	50%	2	100
2	69	F	Left colon	Adenocarcinoma	T4N0MX	2	0%	0	0
3	70	F	Sigmoid	Adenocarcinoma	T3N0MX	3	80%	2	160
4	63	M	Sigmoid	Adenocarcinoma	T3N0MX	3	0%	0	0
5	60	M	Right colon	Adenocarcinoma	T3N0MX	1	0%	0	0
6	66	M	Sigmoid	Adenocarcinoma	T3N0MX	3	0%	0	0
7	52	F	Sigmoid	Adenocarcinoma	T3N1MX	3	70%	2	140
8	50	F	Right colon	Adenocarcinoma	T3N0MX	3	90%	3	270
9	49	M	Right colon	Adenocarcinoma	T3N1MX	3	100%	1	100
10	54	F	Left colon	Adenocarcinoma	T3N0MX	2	90%	3	270
11	86	F	Sigmoid	Adenocarcinoma	T4N0MX	2	100%	2	200
12	60	M	Rectum	Adenocarcinoma	T3N0MX	3	0%	0	0
13	57	M	Cecum	Adenocarcinoma	T3N0MX	3	100%	2	200
14	78	M	Right colon	Adenocarcinoma	T3N1MX	3	90%	2	180
15	75	M	Sigmoid	Tubulo-villous adenoma	T1N0MX	3	10%	1	10
16	91	F	Cecum	Mucinous adenocarcinoma	T3N0M0	2	60%	1	60
17	77	M	Sigmoid	Mucinous adenocarcinoma	T3N2Mx	2	10%	1	10
18	84	F	Cecum	Adenocarcinoma	T3N0Mx	3	40%	1	40
19	85	F	Right colon	Adenocarcinoma	T3N2Mx	2	40%	1	40
20	90	F	Cecum	Adenocarcinoma	T2N0Mx	3	60%	2	120
21	76	M	Right colon	Adenocarcinoma	T3N1M1	2	10%	3	30
22	81	M	Right colon	Tubulo-villous adenoma	TisN0MX	3	40%	2	80
23	74	F	Right colon	Adenocarcinoma	T3N1MX	1	90%	3	270
24	67	M	Right colon	Adenocarcinoma	T3N2Mx	2	0%	0	0
25	79	M	Right colon	Adenocarcinoma	T4N1MX	2	30%	2	60
26	42	F	Sigmoid	Adenocarcinoma	T4N2M1	3	10%	2	20
27	71	M	Right colon	Adenocarcinoma	T4N1Mx	2	50%	1	50
28	89	M	Sigmoid	Adenocarcinoma	T1N0Mx	3	95%	3	285
29	72	F	Cecum	Adenocarcinoma	T2N0Mx	2	100%	4	400
30	72	F	Left colon	Adenocarcinoma	T2N0Mx	2	100%	3	300
31	65	M	Right colon	Tubulo-villous adenoma	T1N0Mx	3	20%	2	40
32	69	F	Left colon	Adenocarcinoma	T3N1Mx	2	10%	1	10
33	45	F	Left colon	Adenocarcinoma	T3N1Mx	3	100%	3	300
34	47	F	Cecum	Adenocarcinoma	T3N1Mx	2	80%	3	240
35	60	F	Left colon	Adenocarcinoma	T3N0Mx	3	100%	4	400
36	70	M	Right colon	Adenocarcinoma	T3N1Mx	2	10%	2	20
37	64	F	Sigmoid	Adenocarcinoma	T3N0Mx	2	5%	1	5

Staining intensity was often variable from place to place and scored as: 0, negative; 1, weak; 2, moderate; 3, strong; 4, intense. Differentiation grade is scored as: 1, well; 2, moderately; 3, poorly differentiated. Results of scores were obtained by multiplying the percentage of positive cells by the intensity; Maximum = 400. Tis: carcinoma in situ; T1, T2, T3, and T4 size and or extend of primary tumor. N0, no regional lymph node involvement; N1, N2, N3, and N4 involvement of regional lymph nodes and/or extent of spread. Mx: distant metastasis cannot be evaluated; Mo: no distant metastasis; M1: distant metastasis is present.